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1

Serial Patterns of Ovarian Cancer Biomarkers in a Prediagnosis Longitudinal Dataset

Blyuss, Oleg, Gentry-Maharaj, Alex, Fourkala, Evangelia-Orania, Ryan, Andy, Zaikin, Alexey, Menon, Usha, Jacobs, Ian, Timms, John F.

Journal:

BioMed Research International

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

2

Consortium analysis of 7 candidate SNPs for ovarian cancer

Susan J. Ramus, Robert A. Vierkant, Sharon E. Johnatty, Malcolm C. Pike, David J. Van Den Berg, Anna H. Wu, Celeste Leigh Pearce, Usha Menon, Aleksandra Gentry-Maharaj, Simon A. Gayther, Richard A. Di

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 251 KB

english, 2008

3

Assessing the malignant potential of ovarian inclusion cysts in postmenopausal women within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a prospective cohort study

A Sharma, A Gentry-Maharaj, M Burnell, E-O Fourkala, S Campbell, N Amso, MW Seif, A Ryan, M Parmar, I Jacobs, U Menon, for the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

Journal:

BJOG: An International Journal of Obstetrics & Gynaecology

Year:

2012

Language:

english

File:

PDF, 202 KB

english, 2012

4

Prevalence, frequency and problem rating of hot flushes persist in older postmenopausal women: impact of age, body mass index, hysterectomy, hormone therapy use, lifestyle and mood in a cross-sectional cohort study of 10 418 British women aged 54–65

MS Hunter, A Gentry-Maharaj, A Ryan, M Burnell, A Lanceley, L Fraser, I Jacobs, U Menon

Journal:

BJOG: An International Journal of Obstetrics & Gynaecology

Year:

2012

Language:

english

File:

PDF, 232 KB

english, 2012

5

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2

Bolton, Kelly L, Gentry-Maharaj, Aleksandra, Wozniak, Eva, Anton-Culver, Hoda, Chang-Claude, Jenny, Cramer, Daniel W, DiCioccio, Richard, Song, Honglin, Ramus, Susan J, Tyrer, Jonathan

Journal:

Nature Genetics

Year:

2009

Language:

english

File:

PDF, 409 KB

english, 2009

6

Common variants at 19p13 are associated with susceptibility to ovarian cancer

Bolton, Kelly L, Tyrer, Jonathan, Song, Honglin, Ramus, Susan J, Notaridou, Maria, Jones, Chris, Sher, Tanya, Gentry-Maharaj, Aleksandra, Wozniak, Eva, Tsai, Ya-Yu

Journal:

Nature Genetics

Year:

2010

Language:

english

File:

PDF, 427 KB

english, 2010

7

Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium

Near, A M, Pearce, C L, Van Den Berg, D J, Ramus, S J, Gentry-Maharaj, A, Menon, U, Gayther, S A, Anderson, A R, Edlund, C K, Wu, A H

Journal:

British Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 163 KB

english, 2009

8

Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer

Quaye, L, Song, H, Ramus, S J, Gentry-Maharaj, A, Høgdall, E, DiCioccio, R A, McGuire, V, Wu, A H, Van Den Berg, D J, Pike, M C

Journal:

British Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 171 KB

english, 2009

9

Screening for ovarian cancer in the general population

Aleksandra Gentry-Maharaj, Usha Menon

Journal:

Best Practice & Research Clinical Obstetrics & Gynaecology

Year:

2012

Language:

english

File:

PDF, 326 KB

english, 2012

10

Vascular endothelial growth factor gene polymorphisms and ovarian cancer survival

Felicity Lose, Christina M. Nagle, Tracy O'Mara, Jyotsna Batra, Kelly L. Bolton, Honglin Song, Susan J. Ramus, Aleksandra Gentry-Maharaj, Usha Menon, Simon A. Gayther, Paul D.P. Pharoah, Mary-Anne Ked

Journal:

Gynecologic Oncology

Year:

2010

Language:

english

File:

PDF, 171 KB

english, 2010

11

Significant endometrial pathology detected during a transvaginal ultrasound screening trial for ovarian cancer

R. Woolas, A. Talaat, M. Anderson, D. Brinkmann, F. Gardner, A. Gentry-Maharaj, A. Ryan, A. Rosenthal, U. Menon, I. Jacobs

Journal:

Gynecologic Oncology

Year:

2011

Language:

english

File:

PDF, 117 KB

english, 2011

12

Risk of epithelial ovarian cancer in asymptomatic women with ultrasound-detected ovarian masses: a prospective cohort study within the UK collaborative trial of ovarian cancer screening (UKCTOCS)

A. Sharma, S. Apostolidou, M. Burnell, S. Campbell, M. Habib, A. Gentry-Maharaj, N. Amso, M. W. Seif, G. Fletcher, N. Singh, E. Benjamin, C. Brunell, G. Turner, R. Rangar, K. Godfrey, D. Oram, J. Hero

Journal:

Ultrasound in Obstetrics & Gynecology

Year:

2012

Language:

english

File:

PDF, 97 KB

english, 2012

13

Recruitment of newly diagnosed ovarian cancer patients proved challenging in a multicentre biobanking study

Nyaladzi Balogun, Aleksandra Gentry-Maharaj, Eva L. Wozniak, Anita Lim, Andy Ryan, Susan J. Ramus, Jeremy Ford, Matthew Burnell, Martin Widschwendter, Sue F. Gessler, Simon A. Gayther, Ian J. Jacobs,

Journal:

Journal of Clinical Epidemiology

Year:

2011

Language:

english

File:

PDF, 93 KB

english, 2011

14

Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

Usha Menon, Aleksandra Gentry-Maharaj, Rachel Hallett, Andy Ryan, Matthew Burnell, Aarti Sharma, Sara Lewis, Susan Davies, Susan Philpott, Alberto Lopes, Keith Godfrey, David Oram, Jonathan Herod, Kar

Journal:

The Lancet Oncology

Year:

2009

Language:

english

File:

PDF, 235 KB

english, 2009

15

Sensitivity of transvaginal ultrasound screening for endometrial cancer in postmenopausal women: a case-control study within the UKCTOCS cohort

Ian Jacobs, Aleksandra Gentry-Maharaj, Matthew Burnell, Ranjit Manchanda, Naveena Singh, Aarti Sharma, Andy Ryan, Mourad W Seif, Nazar N Amso, Gillian Turner, Carol Brunell, Gwendolen Fletcher, Rani R

Journal:

The Lancet Oncology

Year:

2011

Language:

english

File:

PDF, 223 KB

english, 2011

16

Screening of symptomatic women for ovarian cancer

Aleksandra Gentry-Maharaj, Jatinderpal Kalsi, Matthew Burnell, Ranjit Manchanda, Usha Menon

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 83 KB

english, 2012

17

Acceptance of transvaginal sonography by postmenopausal women participating in the United Kingdom Collaborative Trial of Ovarian Cancer Screening

Gentry-Maharaj, A., Sharma, A., Burnell, M., Ryan, A., Amso, N. N., Seif, M. W., Turner, G., Brunell, C., Fletcher, G., Rangar, R., Fallowfield, L., Campbell, S., Jacobs, I., Menon, U.

Journal:

Ultrasound in Obstetrics & Gynecology

Year:

2013

Language:

english

File:

PDF, 89 KB

english, 2013

18

Impact on mortality and cancer incidence rates of using random invitation from population registers for recruitment to trials

Matthew Burnell, Aleksandra Gentry-Maharaj, Andy Ryan, Sophia Apostolidou, Mariam Habib, Jatinderpal Kalsi, Steven Skates, Mahesh Parmar, Mourad W Seif, Nazar N Amso, Keith Godfrey, David Oram, Jonath

Journal:

Year:

2011

Language:

english

File:

PDF, 306 KB

english, 2011

19

Microarray Glycoprofiling of CA125 Improves Differential Diagnosis of Ovarian Cancer

Chen, Kowa, Gentry-Maharaj, Aleksandra, Burnell, Matthew, Steentoft, Catharina, Marcos-Silva, Lara, Mandel, Ulla, Jacobs, Ian, Dawnay, Anne, Menon, Usha, Blixt, Ola

Journal:

Journal of Proteome Research

Year:

2013

Language:

english

File:

PDF, 1.45 MB

english, 2013

20

Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer

Burford, B, Gentry-Maharaj, A, Graham, R, Allen, D, Pedersen, J W, Nudelman, A S, Blixt, O, Fourkala, E O, Bueti, D, Dawnay, A, Ford, J, Desai, R, David, L, Trinder, P, Acres, B, Schwientek, T, Gammer

Journal:

British Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

21

Multiprobabilistic prediction in early medical diagnoses

Nouretdinov, Ilia, Devetyarov, Dmitry, Vovk, Volodya, Burford, Brian, Camuzeaux, Stephane, Gentry-Maharaj, Aleksandra, Tiss, Ali, Smith, Celia, Luo, Zhiyuan, Chervonenkis, Alexey, Hallett, Rachel, Wat

Journal:

Annals of Mathematics and Artificial Intelligence

Year:

2015

Language:

english

File:

PDF, 492 KB

english, 2015

22

Ovarian cancer screening—Current status, future directions

Menon, Usha, Griffin, Michelle, Gentry-Maharaj, Aleksandra

Journal:

Gynecologic Oncology

Year:

2014

Language:

english

File:

PDF, 278 KB

english, 2014

23

T1394 Serum CEACAM1 in the Preclinical Diagnosis of Pancreatic Adenocarcinoma

Sandanayake, Neomal S., Andreola, Fausto, Camuzeaux, Stephane, Sinclair, John, Chapman, Michael H., Webster, George, Gentry-Maharaj, Aleksandra, Menon, Usha, Jacobs, Ian, Pereira, Stephen P., Timms, J

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 77 KB

english, 2010

24

115 INFLUENCE OF BMI AND ALCOHOL ON LIVER-RELATED MORBIDITY AND MORTALITY IN A COHORT OF 108,000 WOMEN FROM THE GENERAL POPULATION FROM UKCTOCS

Trembling, P.M., Apostolidou, S., Parkes, J., Ryan, A., Gentry-Maharaj, A., Tanwar, S., Menon, U., Rosenberg, W.M.

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 565 KB

english, 2013

25

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

Teschendorff, A. E., Menon, U., Gentry-Maharaj, A., Ramus, S. J., Weisenberger, D. J., Shen, H., Campan, M., Noushmehr, H., Bell, C. G., Maxwell, A. P., Savage, D. A., Mueller-Holzner, E., Marth, C.,

Journal:

Genome Research

Year:

2010

Language:

english

File:

PDF, 856 KB

english, 2010

26

Evaluation in pre-diagnosis samples discounts ICAM-1 and TIMP-1 as biomarkers for earlier diagnosis of pancreatic cancer

Jenkinson, C., Elliott, V., Menon, U., Apostolidou, S., Fourkala, O.E., Gentry-Maharaj, A., Pereira, S.P., Jacobs, I., Cox, T.F., Greenhalf, W., Timms, J.F., Sutton, R., Neoptolemos, J.P., Costello, E

Journal:

Journal of Proteomics

Year:

2015

Language:

english

File:

PDF, 330 KB

english, 2015

27

Cancer-associated autoantibodies to MUC1 and MUC4-A blinded case-control study of colorectal cancer in UK collaborative trial of ovarian cancer screening

Pedersen, Johannes W., Gentry-Maharaj, Aleksandra, Nøstdal, Alexander, Fourkala, Evangelia-Ourania, Dawnay, Anne, Burnell, Matthew, Zaikin, Alexey, Burchell, Joy, Papadimitriou, Joyce Taylor, Clausen,

Journal:

International Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 497 KB

english, 2014

28

Reply

Sharma, A., Gentry-Maharaj, A., Burnell, M., Ryan, A., Amso, N. N., Campbell, S., Jacobs, I., Menon, U.

Journal:

Ultrasound in Obstetrics & Gynecology

Year:

2014

Language:

english

File:

PDF, 38 KB

english, 2014

29

Association of skirt size and postmenopausal breast cancer risk in older women: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

Fourkala, E.-O., Burnell, M., Cox, C., Ryan, A., Salter, L. C., Gentry-Maharaj, A., Parmar, M., Jacobs, I., Menon, U.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

30

Validating genetic risk associations for ovarian cancer through the International Ovarian Cancer Association Consortium

Pearce, C L, Near, A M, Van Den Berg, D J, Ramus, S J, Gentry-Maharaj, A, Menon, U, Gayther, S A, Anderson, A R, Edlund, C K, Wu, A H, Chen, X, Beesley, J, Webb, P M, Holt, S K, Chen, C, Doherty, J A,

Journal:

British Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

31

Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis

Cunningham, J M, Vierkant, R A, Sellers, T A, Phelan, C, Rider, D N, Liebow, M, Schildkraut, J, Berchuck, A, Couch, F J, Wang, X, Fridley, B L, Gentry-Maharaj, A, Menon, U, Hogdall, E, Kjaer, S, Whitt

Journal:

British Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 183 KB

english, 2009

32

Early detection of cancer in the general population: a blinded case–control study of p53 autoantibodies in colorectal cancer

Pedersen, J W, Gentry-Maharaj, A, Fourkala, E-O, Dawnay, A, Burnell, M, Zaikin, A, Pedersen, A E, Jacobs, I, Menon, U, Wandall, H H

Journal:

British Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 487 KB

english, 2013

33

Concordance of National Cancer Registration with self-reported breast, bowel and lung cancer in England and Wales: a prospective cohort study within the UK Collaborative Trial of Ovarian Cancer Screening

Gentry-Maharaj, A, Fourkala, E-O, Burnell, M, Ryan, A, Apostolidou, S, Habib, M, Sharma, A, Parmar, M, Jacobs, I, Menon, U

Journal:

British Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 218 KB

english, 2013

34

Histological confirmation of breast cancer registration and self-reporting in England and Wales: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening

Fourkala, E O, Gentry-Maharaj, A, Burnell, M, Ryan, A, Manchanda, R, Dawnay, A, Jacobs, I, Widschwendter, M, Menon, U

Journal:

British Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 404 KB

english, 2012

35

Patient-reporting improves estimates of postoperative complication rates: a prospective cohort study in gynaecological oncology

Iyer, R, Gentry-Maharaj, A, Nordin, A, Liston, R, Burnell, M, Das, N, Desai, R, Gornall, R, Beardmore-Gray, A, Hillaby, K, Leeson, S, Linder, A, Lopes, A, Meechan, D, Mould, T, Nevin, J, Olaitan, A, R

Journal:

British Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 245 KB

english, 2013

36

Serum CA19-9 Is Significantly Upregulated up to 2 Years before Diagnosis with Pancreatic Cancer: Implications for Early Disease Detection

O'Brien, D. P., Sandanayake, N. S., Jenkinson, C., Gentry-Maharaj, A., Apostolidou, S., Fourkala, E.-O., Camuzeaux, S., Blyuss, O., Gunu, R., Dawnay, A., Zaikin, A., Smith, R. C., Jacobs, I. J., Menon

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 773 KB

english, 2015

37

Peptides Generated Ex Vivo from Serum Proteins by Tumor-Specific Exopeptidases Are Not Useful Biomarkers in Ovarian Cancer

Timms, J. F., Cramer, R., Camuzeaux, S., Tiss, A., Smith, C., Burford, B., Nouretdinov, I., Devetyarov, D., Gentry-Maharaj, A., Ford, J., Luo, Z., Gammerman, A., Menon, U., Jacobs, I.

Journal:

Clinical Chemistry

Year:

2010

Language:

english

File:

PDF, 492 KB

english, 2010

38

Predictors of complications in gynaecological oncological surgery: a prospective multicentre study (UKGOSOC—UK gynaecological oncology surgical outcomes and complications)

Iyer, R, Gentry-Maharaj, A, Nordin, A, Burnell, M, Liston, R, Manchanda, R, Das, N, Desai, R, Gornall, R, Beardmore-Gray, A, Nevin, J, Hillaby, K, Leeson, S, Linder, A, Lopes, A, Meechan, D, Mould, T,

Journal:

British Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 183 KB

english, 2015

39

Use and perceived efficacy of complementary and alternative medicines after discontinuation of hormone therapy

Gentry-Maharaj, Aleksandra, Karpinskyj, Chloe, Glazer, Clara, Burnell, Matthew, Ryan, Andy, Fraser, Lindsay, Lanceley, Anne, Jacobs, Ian, Hunter, Myra S., Menon, Usha

Journal:

Year:

2015

Language:

english

File:

PDF, 204 KB

english, 2015

40

Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk

Pearce, C. L., Doherty, J. A., Van Den Berg, D. J., Moysich, K., Hsu, C., Cushing-Haugen, K. L., Conti, D. V., Ramus, S. J., Gentry-Maharaj, A., Menon, U., Gayther, S. A., Pharoah, P. D. P., Song, H.,

Journal:

Human Molecular Genetics

Year:

2011

Language:

english

File:

PDF, 218 KB

english, 2011

41

Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival

Quaye, L., Dafou, D., Ramus, S. J., Song, H., Gentry-Maharaj, A., Notaridou, M., Hogdall, E., Kjaer, S. K., Christensen, L., Hogdall, C., Easton, D. F., Jacobs, I., Menon, U., Pharoah, P. D.P., Gaythe

Journal:

Human Molecular Genetics

Year:

2009

File:

PDF, 21 KB

2009

42

Socioeconomic indicators of health inequalities and female mortality: a nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

Bailey, Katharine, Ryan, Andy, Apostolidou, Sophia, Fourkala, Evangelia, Burnell, Matthew, Gentry-Maharaj, Aleksandra, Kalsi, Jatinderpal, Parmar, Max, Jacobs, Ian, Pikhart, Hynek, Menon, Usha

Journal:

BMC Public Health

Year:

2015

Language:

english

File:

PDF, 707 KB

english, 2015

43

Predictive Value of Symptoms for Ovarian Cancer: Comparison of Symptoms Reported by Questionnaire, Interview, and General Practitioner Notes

Lim, A. W. W., Mesher, D., Gentry-Maharaj, A., Balogun, N., Jacobs, I., Menon, U., Sasieni, P.

Journal:

JNCI Journal of the National Cancer Institute

Year:

2012

Language:

english

File:

PDF, 349 KB

english, 2012

44

Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening

Menon, U., Ryan, A., Kalsi, J., Gentry-Maharaj, A., Dawnay, A., Habib, M., Apostolidou, S., Singh, N., Benjamin, E., Burnell, M., Davies, S., Sharma, A., Gunu, R., Godfrey, K., Lopes, A., Oram, D., He

Journal:

Journal of Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 751 KB

english, 2015

45

Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition

Davis, S. J., Sheppard, K. E., Anglesio, M. S., George, J., Traficante, N., Fereday, S., Intermaggio, M. P., Menon, U., Gentry-Maharaj, A., Lubinski, J., Gronwald, J., Pearce, C. L., Pike, M. C., Wu,

Journal:

Molecular Cancer Therapeutics

Year:

2015

Language:

english

File:

PDF, 4.02 MB

english, 2015

46

ABRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival

Anjum, Shahzia, Fourkala, Evangelia-Ourania, Zikan, Michal, Wong, Andrew, Gentry-Maharaj, Aleksandra, Jones, Allison, Hardy, Rebecca, Cibula, David, Kuh, Diana, Jacobs, Ian J, Teschendorff, Andrew E,

Journal:

Genome Medicine

Year:

2014

Language:

english

File:

PDF, 1.90 MB

english, 2014

47

Association of serum sex steroid receptor bioactivity and sex steroid hormones with breast cancer risk in postmenopausal women

Fourkala, E.-O., Zaikin, A., Burnell, M., Gentry-Maharaj, A., Ford, J., Gunu, R., Soromani, C., Hasenbrink, G., Jacobs, I., Dawnay, A., Widschwendter, M., Lichtenberg-Frate, H., Menon, U.

Journal:

Endocrine Related Cancer

Year:

2012

Language:

english

File:

PDF, 134 KB

english, 2012

48

Preanalytic Influence of Sample Handling on SELDI-TOF Serum Protein Profiles

Timms, J. F., Arslan-Low, E., Gentry-Maharaj, A., Luo, Z., T'Jampens, D., Podust, V. N., Ford, J., Fung, E. T., Gammerman, A., Jacobs, I., Menon, U.

Journal:

Clinical Chemistry

Year:

2007

Language:

english

File:

PDF, 839 KB

english, 2007

49

Evaluation of serum CEA, CYFRA21-1 and CA125 for the early detection of colorectal cancer using longitudinal preclinical samples

Thomas, D S, Fourkala, E-O, Apostolidou, S, Gunu, R, Ryan, A, Jacobs, I, Menon, U, Alderton, W, Gentry-Maharaj, A, Timms, J F

Journal:

British Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 535 KB

english, 2015

50

Decreased serum thrombospondin-1 levels in pancreatic ductal adenocarcinoma patients: an early indicator of disease or diabetes mellitus development?

Jenkinson, Claire, Elliott, Victoria, Evans, Anthony, Oldfield, Lucy, O'Brien, Darragh, Apostolidou, Sophia, Gentry-Maharaj, Aleksandra, Fourkala, Evangelia-O., Jacobs, Ian, Menon, Usha, Cox, Trevor,

Journal:

Year:

2015

Language:

english

File:

PDF, 45 KB

english, 2015